The White House recently issued an executive order establishing the “Genesis Mission,” a US Department of Energy (DOE)-led initiative aimed at accelerating scientific discovery using advanced AI. Nuclear energy was specifically highlighted as one of the key scientific areas for advancement.
Overview
The Genesis Mission aims to unify DOE supercomputers, secure cloud-based AI environments, and federal scientific datasets into the American Science and Security Platform. This platform will enable AI-driven research across priority technology domains, including nuclear fission and fusion energy, advanced manufacturing, biotechnology, and critical materials.
Possible Nuclear Implications
For the nuclear sector, the Genesis Mission signals a major federal push to leverage AI for “nuclear fission and fusion energy,” which the executive order explicitly identifies in Section 4(a)(iv) as a priority national science and technology domain, thereby positioning AI-enabled reactor design, fusion research, materials modeling, and autonomous experimentation as central targets for accelerated federal research and development activity. DOE is required to inventory resources, identify datasets, and establish partnerships—including with private-sector cloud and computing providers—on an accelerated timeline. Additionally, the executive order increased push for data centers may drive market demands for new nuclear power generation.
Read more about the executive order here.